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NGF-beta, human recombinant

A factor critical for the survival & maintenance of sympathetic and sensory neurons
Catalog #: 4303R
SKU-Size Size Price Qty
4303R-20 20 μg
$185.00
4303R-100 100 μg
$595.00
4303R-1000 1 mg
$3,350.00
More Sizes Get Quote

Product Details

Alternate Name β Polypeptide, NGF, NGFB, HSAN5, β-NGF, MGC161426, MGC161428.
Gene Symbol NGF
Gene ID 4803
Accession # P01138
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and then lyophilized with no additives.
Molecular Weight 13.6 kDa
Purity by SDS-PAGE ≥97%
Purity by ≥97%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the ability to stimulate neurite growth in chick E9 DRG cells is <1.0 ng/ml.
Reconstitution Instructions Reconstituted human NGF-β should be stored in working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid freeze/thaw cycles.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NGF-β is a dimer, formed by two identical 119 amino acid subunits, which is held together by strong hydrophobic interactions. Recombinant human NGF-b produced in CHO cells is a homodimer, glycosylated, polypeptide chain containing 2 identical 119 amino acids and having a molecular weight of 16.95 kDa. The protein is purified by proprietary chromatographic techniques.


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