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Nexturastat A

A potent HDAC6 inhibitor
Catalog #: 2098
$130.00

Product Details

Cat # +Size 2098-1
Size 1 mg
Alternate Name 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide
Appearance Off-white solid
CAS # 1403783-31-2
Molecular Formula C₁₉H₂₃N₃O₃
Molecular Weight 341.4
Purity ≥98% by HPLC
Solubility DMSO
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5.02 ± 0.60 nM). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC11, respectively. Nexturastat A also displays antiproliferative effects against melanoma cells.


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