Researchers suggest IgA antibodies are better at neutralising SARS-CoV-2
August 2020 | Science News
Scientists have developed a novel secretory immunoglobulin A (sIgA) serotype antibody that binds more effectively to the spike protein of SARS-CoV-2 than some IgG antibodies.
New discovery about STING protein could lead to improved cancer immunotherapies
August 2020 | Science News
STING was first identified about a decade ago as a protein that can activate the type I interferon (IFN) response in immune cells. The IFN response is a powerful and well-studied immune reaction that the body uses to fight everything from viruses and bacteria to rogue tumor cells.
Testing the Toxicity of CDK Inhibitors and Radiotherapy
August 2020 | Science News
A study showed that the radiotherapy alongside the three CDK inhibitors palbociclib, ribociclib, or abemaciclib, had achieved local control of the malignancy & with no abnormal toxicity.
A Key Juncture Between Diabetes and Heart Repair
August 2020 | Science News
The team of scientist investigating how empagliflozin, an SGLT2 inhibitor, could prevent the scarring often seen post-heart attack. They focused on the relationship between empagliflozin and a protein called GTP cyclohydrolase 1 (GCH1). GCH1 deficiency is associated with hypertension and cardiac dysfunction.
Tumor Growth Slowed Down by Restricting Amino Acid Metabolism
August 2020 | Science News
Scientists showed that by restricting the dietary amino acids serine and glycine, which in turn targeted the serine synthesis enzyme phosphoglycerate dehydrogenase, induced tumor cells to produce a toxic lipid that slows cancer progression in mice.
Metastasis-preventing drug target for pancreatic cancer identified
August 2020 | Science News
A protein called PPP1R1B has been revealed as a drug target for pancreatic cancer as it stopped the metastasis of tumours in mice.
A New Role for Actin Revealed by Imaging Method
August 2020 | Science News
Actin mediates an important function of mitochondrial fission. Proper imaging technique provides a better understanding of mitochondrial dysfunction, which has been linked to cancer, aging, and neurodegenerative diseases.
Biomarker for Heart Disease Captured by Novel Nanoparticle Technology
August 2020 | Science News
Scientists have developed a technique combining sticky nanoparticles with high-precision protein measurement effectively captures and measures various forms of the protein cardiac troponin I, or cTnI, a biomarker of heart damage currently used to help diagnose heart attacks and other heart diseases.
Using organoids to improve chemotherapy for advanced stages of colon and appendiceal cancer
August 2020 | Science News
Scientists showed that with the organoid platform, they can quantify the impact of each drug in killing cancer cells.
New Anti-Alzheimer's Compound Reverses Memory Decline in Mice
August 2020 | Science News
Researchers found that the Alzheimer’s patients had higher amounts of the FASN protein, they also showed that CMS121 lowered levels of a lipid-producing molecule called fatty acid synthetase (FASN), which, in turn, lowered levels of lipid peroxidation.
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.