Novel Toolkit Reprograms Skin Cells into Different Kinds of Neurons
May 2018 | Science News
Scientists at The Scripps Research Institute say they have put together what they call a "neuronal cookbook" for turning skin cells into different types of neurons.
Heart failure: The Alzheimer's disease of the heart?
May 2018 | Science News
Protein clumping may contribute to heart failure development and could be used as a diagnostic tool for testing therapies or disease progression
Date.
Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome
May 2018 | Science News
DNA methylation, is known to vary in different cell types or at different stages of cellular development, but the details of how cells regulate exactly where to put DNA methylation marks have remained unclear.
Protein in Breast Cancer Found to Be Essential for Metastasis
May 2018 | Science News
Investigators at the Montreal Clinical Research Institute (IRCM) and University of Montreal have just uncovered an essential protein that, once deactivated, could prevent the development of metastases in the aggressive HER2-positive (HER+) breast cancer.
Blocking Single Gene Prevents Obesity in Fat-Fed Mice
May 2018 | Science News
Studies in mice by scientists at the University of Copenhagen in Denmark have now shown how it is possible to genetically prevent animals from becoming obese, by deleting a single enzyme, called nicotinamide phosphoribosyltransferase (NAMPT), in the animals’ adipose tissues.
Treating Migraines with Less Side-Effects
May 2018 | Science News
Scientists have stumbled upon a side-effect free treatment option for chronic migraines. The discovered drug is erenumab which works against migraines to inhibit pain signals by targeting a receptor for calcitonin gene-related peptide (CGRP).
CRISPR “One Shot" Cell Therapy for Hemophilia Developed
May 2018 | Science News
Scientists at the Salk Institute have combined CRISPR-Cas9 gene editing with stem cell technology to generate a one-time, autologous cell therapy for the genetic blood clotting disorder hemophilia B. In vivo tests showed that gene-edited, stem cell–derived liver cells remained viable and functional in hemophiliac mice for nearly a year, after just a single injection.
Scientists discover new target in the treatment of pulmonary hypertension
May 2018 | Science News
In a recent study, scientists found that eliminating the FoxM1 gene could improve outcomes for patients with pulmonary hypertension.
Paralyzed Patients Regain Function After Spinal Stimulation
April 2018 | Science News
Once a person has suffered a spinal cord injury, there isn't much to be done except to learn how to live with paralysis and loss of function. That could change, thanks to the work of a team of scientists at UCLA. A study involving spinal stimulation has resulted in patients, some of them completely paralyzed, to regain the movement of their hands and fingers.
Scientists discover potential therapeutic target for devastating premature aging disease
April 2018 | Science News
Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterized by premature aging.
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