Isolating a Neurological Protein May Protect Against Inflammatory Disorders
May 2018  |  Science News
The immune cells known as macrophages are categorized as M1 or M2 inflammatory macrophages. The M1 cells participate in the inflammatory response that destroys invading organisms, while M2 cells hold anti-inflammatory properties that are believed to protect against inflammatory diseases.
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Drug Repurposing: Antimalarial Drug Treats Ovarian Cancer in Patient
May 2018  |  Science News
Dr. Muggia's patient surprised doctors with immediate and lasting response to the ovarian cancer treatment. Three years later, and the patient is ovarian-cancer free and dermatomyositis free. The follow-up results were also seen to have no evidence of the symptoms exhibited by these two diseases.Read the Full Article from Labroots
Tumor-Suppressor Genes Turned Off by 3' UTR Shortening
May 2018  |  Science News
The team, led by scientists at The University of Texas Medical Branch (UTMB) at Galveston and Baylor College of Medicine, found that losing a section of mRNA that was previously thought to transform normal cells into cancerous ones actually acts by blocking the body's ability suppress the formation of tumors.
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Advances in Fragment-Based Drug Discovery
May 2018  |  Science News
Screening the fragment library allows you to uncover structural insights, enabling you to identify the interaction of multiple weak affinity fragment hits with the protein target, guiding medicinal chemistry optimization.
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Signaling Pathways Linking Stem Cells and Macrophages May Play Role in Breast Cancer
May 2018  |  Science News
Scientists from the University of Pennsylvania say they have discovered a new signaling exchange that mediates normal mammary gland development by regulating the mammary stem cell niche, which was not previously understood.
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Colon Cancer Cells Use RNA Strands to Evade Cell Death
May 2018  |  Science News
Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth. .
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Microbes Affect Brain Cells’ Activities in Mice with Multiple Sclerosis
May 2018  |  Science News
Researchers find a link between molecules released by commensal bacteria and the degree of inflammation in a mouse model of MS.
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Essential fats in diet may regulate protein secretion in muscles by altering gene expression
May 2018  |  Science News
A new study reveals that essential fats in the diet may play a role in regulating protein secretion in the muscles by changing the way genes associated with secretion act.
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Tumor-like spheres help scientists discover smarter cancer drugs
May 2018  |  Science News
The technique makes use of tiny, three-dimensional ball-like aggregates of cells called spheroids.
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Successful Neural Stem Cell Therapy Without Immunosuppression
May 2018  |  Science News
In a new study, UCSD scientists successfully designed neural precursor cells from induced pluripotent stem cells (iPSCs). Senior author Martin Marsala, MD, lauds human iPSCs as the “ultimate source of cells to be used in future clinical trials for treatment of spinal cord and central nervous system injuries in a syngeneic or allogeneic setting.”
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