Reclaim the Tumor Microenvironment via “Immunoforming”
July 2018 | Science NewsCellular 'garbage disposal' has another job
July 2018 | Science News
Johns Hopkins researchers have found that the cellular "garbage disposal," known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important proteins to neuronal development.
Researchers use gene therapy to cure obesity and type 2 diabetes in mice
July 2018 | Science News
A single administration of an adeno-associated viral vector (AAV) carrying the FGF21 (Fibroblast Growth Factor 21) gene, resulted in genetic manipulation of the liver, adipose tissue or skeletal muscle to continuously produce the FGF21 protein.
AF Treatment Zaps Faulty Heart Tissue
July 2018 | Science News
Treating atrial fibrillation (AF), the most common type of arrhythmia, with what was previously a last-resort therapeutic approach will help reduce the risk of death and stroke in the long-run. From the University of California - Davis Health System, scientists show how cardiac ablation in addition to medication can be beneficial for AF patients.
TRAF7 Mutation Responsible for Mysterious Disorder
June 2018 | Science News
A multisystem developmental disorder with specific symptoms shared by seven patients had gone unexplained, but a new genetic sequencing study may provide at least part of an answer. From the Baylor College of Medicine, scientists discuss how mutations in a gene called TRAF7 (TNF receptor association factor 7) could be causing this mysterious condition.
Key Protein Mediating Inflammatory Response Discovered
June 2018 | Science News
Investigators from the University of Illinois at Chicago (UIC) have identified a protein that they believe is critical for activating inflammation. An ion channel called TWIK2 that spans the membrane of immune cells—presents a new target for the development of drugs that can restrain overblown inflammatory responses.
Potential Drug May 'Freeze' Cancer Cells
June 2018 | Science News
New research study is bringing hope to cancer patients undergoing the early stages of the disease, published in the journal Nature Communications, the study examines a drug compound that can put a stop onto cancer motility.
A New Kind of Skin for Prosthetic Hands
June 2018 | Science News
Researchers at Johns Hopkins University have used that illusion to engineer an electronic skin that can be layered on top of prosthetic limbs. The benefit of what the team is calling, "e-dermis" is that patients can have the sense of touch returned, even though their hand or arm is gone.
Oxygen-Starved Cancer Cells Languish without Aspartate
June 2018 | Science News
Deep inside tumors, where oxygen is scarce, cancer cells are reduced to scrounging metabolites from their surroundings. A particularly valuable metabolite happens to be aspartate. If oxygen-starved cancer cells can pick up aspartate, report scientists based at Rockefeller University, they survive, grow, and proliferate despite their suffocating conditions.
Cancer Metastasis Hobbled by New Compound
June 2018 | Science News
Researchershave developed a small-molecule drug that can stop the movement of cancer cells and so prevent their spread to other areas of the body. Early tests in mouse models of different human cancers showed that the orally administered compound KBU2046 inhibited metastasis, reduced bone destruction, and prolonged survival, without any evident toxicity.
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.