Researchers stimulate neural recovery in model of traumatic brain injury
August 2018  |  Science News
Researchers from the University of Georgia have replicated the effects of traumatic brain injury (TBI) and electrically stimulated neural recovery, using stem cell-derived neurons grown in a petri dish.
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HIF1A Identified as Potential Target for Treating Myelodysplastic Syndromes
August 2018  |  Science News
HIF1A, a transcription factor, plays a vital role in how cells respond to metabolic changes and oxygen, and it affects the function of more than a thousand genes. This includes a vital role in regulating biological functions in blood-cell-making hematopoietic stem cells in bone marrow.
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Stressed, toxic, zombie cells seen for 1st time in Alzheimer's
August 2018  |  Science News
Tau protein accumulation is common across 20 human brain diseases. Researchers have found stressed, senescent cells in Alzheimer's disease, and established a link between tau tangles and this cell stress. The scientists used a senolytic therapy to clear the senescent cells and tau tangles in Alzheimer's mice, which improved both brain function and structure.
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Genetic Diseases More Severe with Adverse Coding, Regulatory Variant Combos
August 2018  |  Science News
Scientists confirmed that modified penetrance of coding variants by cis-regulatory variation contributes to disease risk. It presents evidence that joint regulatory and coding variant effects are an important part of the genetic architecture of human traits and contribute to modified penetrance of disease-causing variants.
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Researchers create the world’s first artificial retina
August 2018  |  Science News
Scientists have developed an ultrathin artificial retina that could provide a superior alternative to the visual implants currently available to the blind.
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Parkinson’s Diagnosis Could Be in the Eyes of the Holder
August 2018  |  Science News
Scientists are suggesting that a patient’s eyes may be a window to the brain for people with early Parkinson's disease (PD). The new study—published recently in Neurology through an article titled “Retinal thinning associates with nigral dopaminergic loss in de novo Parkinson disease”found that the thinning of the retina, the lining of nerve cells in the back of the eye, is linked to the loss of dopaminergic brain cells, a hallmark for PD.
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Scientists uncover key control mechanism of DNA replication
August 2018  |  Science News
To ensure faithful duplication of the cell's genetic blueprints, replication begins at distinctly different times as well as locations. Each cell's genetic material is arranged into specific "files" called chromosomes. The "tabs" labeling these files are called telomeres—they help ensure the DNA sequences begin and end in the correct order and at the correct times.
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Female vs. Male: The Immune Response
August 2018  |  Science News
A genetic conflict in the immune response in animals between male and females, with central immune system genes varying more highly in females and lower in males.
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Stress hormone is key factor in failure of immune system to prevent leukemia
August 2018  |  Science News
The human stress hormone cortisol has been identified by scientists at the University of Kent as a key factor when the immune system fails to prevent leukemia taking hold.
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Kidney Cancer Biomarker Predicts Disease Risk and Survival
August 2018  |  Science News
In a new study, the researchers showed that kidney-injury-molecule-1 (KIM-1)—which can be detected in the urine and blood—substantially helped distinguish between those who went on to develop kidney cancer from those who did not.
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