Molecular switches are not just 'on' or 'off'
September 2018 | Science News
It is not always easy to see if a switch is on or off! A new study shows that the same can be true of a molecular switch. This knowledge gives a new insight into the molecular switches, the GTPases, many of which have medical potential.
Memories Strengthened through Epigenetic Mechanism
September 2018 | Science News
Researchers discovered a novel mechanism that links epigenetic changes in the hippocampus of the rat brain that controls downstream regulation of translation in brain neurons during fear memory reconsolidation. Understanding how memories form and are retrieved has applications to psychiatric, neurological, and neurodegenerative disorders, and may be helpful to attenuate maladaptive memories in psychiatric disorders.
Bee Venom Takes the Sting Out of Eczema
September 2018 | Science News
The results of studies by scientists in Korea and Australia suggest that bee venom (BV) may represent an effective treatment for atopic dermatitis (eczema),
Encapsulating biomedical micromotors in traditional pill form
September 2018 | Science News
scientists report that they have found a way to encapsulate micromotors into pills. The pill's coating protects the devices as they traverse the digestive system prior to releasing their drug cargo.
Like a zipper -- how cells form new blood vessels
September 2018 | Science News
Blood vessel formation relies on the ability of vascular cells to move while remaining firmly connected to each other. This enables the vessels to grow and sprout without leaking any blood. Scientists now describe how this works. In this process, the cytoskeleton pushes the cell forward, while an adhesion protein subsequently closes the gap to the neighboring cell, like a zipper.
B Cells Control Connective Tissue Disorder Scleroderma
August 2018 | Science News
B cells are a critical player in the immune response, they mature into antibody-producing cells as well as presenting antigens and secreting cytokines . Study found that B cells play a reciprocal role in the pathogenesis of scleroderma, with both pathogenic and protective functions
Stems Cells Used as Delivery Truck for Brain Cancer Drug
August 2018 | Science News
The cells are like a FedEx truck that will get you to a particular location, and (deliver) potent cytotoxic agents directly into the tumor," explains senior study investigator Shawn Hingtgen, Ph.D., an assistant professor in the UNC School of Medicine.
New way to break cancer's vicious cycle
August 2018 | Science News
By blocking NUAK2 protein, either by drugs or by muting the gene that encodes it, the researchers were able to slow down expansion of breast cancer cells in the dish and to shrink breast tumours in mice, respectively. A similar approach could target high-grade tumours in patients.This study reveals how some tumors fuel their own growth and how stopping this vicious cycle could lead to new treatments.
New Brain Cell Has Unique Shape, Behavior, Gene Signature
August 2018 | Science News
A new kind of neuron, possibly unique to humans, has been discovered based on transcriptomic and morphophysiological evidence. Called the rosehip neuron because it resembles a rose deprived of its petals, the newfound circuit element seems to refine signal inhibition in localized regions of the brain.
Measuring the tension of a cell with a molecule
August 2018 | Science News
Researchers have created a new fluorescent molecule with which they were able to measure the tension of a cellular membrane, and, in the process, discover how cells adjust their surface area relative to their volume.
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.