Drug Duo Treats ALS – On A Chip
October 2018 | Science News
A study just published in Science Advances shows that two drugs already FDA-approved for other diseases, when teamed, halt neuron death and bolster muscle contraction in an “organ-on-a-chip” model of ALS.
Micropeptide Discovery May Lead to New Gene Therapy for Heart Failure
October 2018 | Science News
The micropeptide works by preventing calcium dysregulation and remodelling of the heart and could be a promising new gene therapy target to treat heart failure, say the researchers.
Predicting Autism With EEG?
October 2018 | Science News
Scientists were successful in predicting autism in children as young as three months old by using algorithms to analyze the readings collected from study volunteers.
Researchers at the Children’s Hospital of Philadelphia and the University of Pennsylvania have successfully used prenatal gene editing to prevent a fatal metabolic disorder in an animal model.
October 2018 | Science News
In a mouse model, the researchers used CRISPR-Cas9 and base editor 3 (BE3) gene-editing tools to target a gene that controls cholesterol levels and reduce cholesterol in utero.
New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
October 2018 | Science News
Researchers at the Faculty of Pharmacy have developed PeptiENV, a cancer vaccine platform, which can be used to improve the therapeutic efficacy of oncolytic enveloped viruses currently in clinical use. With the help of this new cancer vaccine platform, the activation of the human immune response against cancer cells becomes significantly more effective.
Appetite-suppressant drug reduces diabetes risk and increases remission rates of blood sugar
October 2018 | Science News
The appetite-suppressant drug lorcaserin decreases risk of developing diabetes and increases the rates of remission of high blood sugar. Lorcaserin also reduces the risk of kidney complications due to diabetes in obese and overweight patients.
Brain Defects Linked to Growth Factor Hormone
September 2018 | Science News
Investigators at the Medical University of South Carolina (MUSC) made a recent discovery that could provide crucial insights into structural changes within the brain and have a profound impact on dietary habits to improve overall brain health. The new study showed that high levels of fibroblast growth factor 23 (FGF23) were associated with structural changes in the brain's frontal lobes.
In clinical trials, new antibody therapy controls HIV for months after treatment
September 2018 | Science News
A new clinical trial shows that broadly neutralizing antibodies can suppress HIV for up to four months, far longer than currently available drugs.
Membrane Channel Critical to Blood Pressure Control Visualized for First Time
September 2018 | Science News
Scientists report that they have visualized the three-dimensional structure of a membrane channel that's critical in controlling blood pressure.
New cause of brain bleeds identified
September 2018 | Science News
The researchers found that brain endothelial cells, the cells that line blood vessels of the brain, have the capacity for engulfing red blood cells and depositing them outside the blood vessels and into the substance of the brain, without requiring a disruption of the vasculature.
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