D-serine could protect against epileptic seizures
October 2020 | Science News
Scientist identified the mechanism through which temporal lobe epileptic seizures are sparked and that D-serine can interfere with this process, preventing seizures.
Telomere-Preserving RNA Guided by DNA Repair Enzyme
October 2020 | Science News
TERRA (telomeric-repeat-containing RNA) helps to regulate the length and function of telomeres. RAD51 is a well-known enzyme that is involved in the repair of broken DNA molecules. The protein also seems to help TERRA stick to telomeric DNA, to form an ‘RNA-DNA hybrid’ molecule.
Researchers Investigate Neural Crest Cell Migration in Hirschsprung Disease
October 2020 | Science News
Scientists say that during the development, neural crest cells, the precursors of neurons in the enteric nervous system, migrate throughout the digestive tract to provide innervation.
Researchers Solve Key Problem for Cancer Immunotherapy
October 2020 | Science News
Researchers found that liver tumors were able to change which genes were expressed in regulatory T cells (immune cells that suppress the immune response also known as 'Tregs') and from there, multiple other immune system cells too.
New Immunotherapy Drug Effective Against Lung Cancer
October 2020 | Science News
Tecentriq (atezolizumab) is a checkpoint inhibitor drug and works by targeting a protein called PD-L1 that lies on the surface of tumor cells and signals the body’s immune system T cells not to attack certain pathogens.
Brain’s Resident Immune Cells Found to Play Key Role in Regulating Behavior
October 2020 | Science News
Researchers found that microglia are “critical modulators” of neuronal activity and associated behavioral responses in mice. The microglia can sense extracellular ATP, which draws them toward the active neurons. The microglia then break ATP down to generate adenosine, which acts on adenosine receptors on the surface of active neurons to suppress their activity and prevent excessive activation.
Researchers Confirm Link Between Alzheimer's and Sleep Apnea
September 2020 | Science News
Scientists find Alzheimer's-like amyloid plaques in the brains of people with clinically-verified obstructive sleep apnea.
Dual CAR T Cell Immunotherapy Fights HIV Infection in Humanized Mice
September 2020 | Science News
CAR T cells are a powerful immunotherapy, currently used in cancer treatments, in which a patient’s own immune T cells are engineered to express Chimeric Antigen Receptors (CARs). These CARs re-program the T cells to recognize and eliminate specific diseased or infected cells, such as cancer cells or, potentially, HIV-infected cells.
Mystery glycoprotein could prevent respiratory distress
September 2020 | Science News
According to researchers, the DMBT1S8 molecule can halt inflammation in the respiratory tract through its interaction with the Siglec-8 receptor on immune cells.
Blood Vessels on a Chip Test Clotting
September 2020 | Science News
Biomedical engineers have made a breakthrough in the field, inventing a microfluidic device that mirrors the intricate structures of the vasculature, giving clinicians the power to analyze the coagulation potential of a blood sample faster, more efficiently, and at a much lower cost than existing technologies.
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