Functional Cells That Make Insulin Successfully Grown in the Lab
February 2019 | Science News
Scientists can now generate insulin-producing cells that look and act a lot like the pancreatic beta cells we have in our bodies. This is a critical step towards our goal of creating cells that could be transplanted into patients with diabetes, says Matthias Hebrok, Ph.D., the Hurlbut-Johnson Distinguished Professor in Diabetes Research at UCSF and director of the UCSF Diabetes Center.
More Than 100 New Gut Bacteria Discovered in Human Microbiome
February 2019 | Science News
Scientists working on the gut microbiome have discovered and isolated more than 100 completely new species of bacteria from healthy people's intestines.
An Algorithm to Predict the Age of Your Lab Mice
February 2019 | Science News
Researchers develop an app that can estimate the biological age of a rodent from its mug shot—and could give a boost to the science of human aging in the process.
Gum Disease Could Drive Alzheimer’s: Study
January 2019 | Science News
An enzyme of the bacteria Porphyromonas gingivalis has been found in the brains of patients with the disorder, and causes neurodegeneration in mice.
Pediatric Brain Tumors Shrink from Epigenome Targeted Therapy
January 2019 | Science News
Researchers have just released their findings from a new study that shows how a targeted therapy, which blocks a protein called Lysine demethylase 1 (LSD1), was able to shrink tumors in mice with a form of pediatric brain cancer known as medulloblastoma.
Groundbreaking tool helps visualize neuronal activity with near-infrared light
January 2019 | Science News
A new, groundbreaking tool for visualizing neural activity has implications for understanding brain functions and disorders, according to new research. The tool, named NIR-GECO1, identifies when an individual neuron is active by monitoring for the presence or absence of calcium ions.
Synthetic flaxseed derivative helps heart function in septic mice
January 2019 | Science News
Sepsis is a life-threatening condition that develops in response to infection. One of its major complications is cardiovascular dysfunction. Now, scientists show that a novel synthetic compound derived from flaxseed can reverse this and improve heart function in mice with sepsis.
Protein Changes Detected in Blood Years Before Alzheimer’s Onset
January 2019 | Science News
Levels of a protein called neurofilament light chain increase in the blood and spinal fluid of some Alzheimer’s patients 16 years before they develop symptoms. This observation could pave the way for a blood test to predict disease progression in people with a genetic predisposition to developing the neurodegenerative disorder.
Cancer Fighting T Cells Produced Continuously through New Method
January 2019 | Science News
T cells are cells of the immune system that fight infections, but also have the potential to eliminate cancer cells. The ability to create them from self-renewing pluripotent stem cells using a technique generated by UCLA scientists could lead to new approaches to cancer immunotherapy and could spur further research on T cell therapies for viral infections such as HIV, and autoimmune diseases.
Study reveals potential pathway for endothelial cells to avoid apoptosis
January 2019 | Science News
Scientists investigated the mechanism underlying endothelial cell resistance to TNFα-induced apoptosis, an important mechanism of cell death in inflammatory conditions.
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