Colorectal Cancer Stem Cell Growth Driven by High-Fat Diet and Altered Bile Acid Profile
February 2019 | Science News
Scientists have suggested how high-fat diets may fuel the early development of colorectal cancer in people who have a common genetic mutation. Findings from the studies in mouse models and human cells, and reported in Cell, indicate that a high-fat diet and genetics combine to change bile acid balance in the gut, which in turn impacts on bile acid hormonal signaling to stem cells and lets potentially cancerous cells survive.
Young Bone Marrow Rejuvenates Aging Mouse Brains, New Study Finds
February 2019 | Science News
A new study has found that transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities.
Scientists develop new AI platform for monitoring and predicting ALS progression
February 2019 | Science News
Scientists have developed a new artificial intelligence (AI) platform for monitoring and predicting progression of neurodegenerative diseases to help identify markers for personalized patient care and improve drug development.
Alveoli Finding May Offer New Opportunities to Treat Lung Damage
February 2019 | Science News
The researchers say that investigating the fetal signaling pathways active in this biological event may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.
Can we repair the brain? The promise of stem cell technologies for treating Parkinson's disease
February 2019 | Science News
Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.
UVA researcher to present updates on new artificial pancreas at AAAS Annual Meeting
February 2019 | Science News
The artificial pancreas uses an advanced computer algorithm to automatically monitor and regulate blood-sugar levels in people with type 1 diabetes, with the goal of eliminating the need for them to stick their fingers multiple times daily to check their blood-sugar levels and to manually inject insulin.
Protein Biomarker Differentiates between Cystitis and Bladder Cancer
February 2019 | Science News
AHNAK2 differentiates between chronic cystitis and a non-muscle invasive-type BC, which is challenging to diagnose. Scientists describe this new diagnostic procedure, which is label-free, automated, observer-independent, and as sensitive and specific as established histopathological methods.
Researchers 3D bio-print a model that could lead to improved anticancer drugs and treatments
February 2019 | Science News
Researchers create the first 3D in vitro model capable of isolating specific metastatic cells. University of Minnesota researchers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3D in vitro model (i.e. in a culture dish rather than in a human or animal).
Pancreatic Cancer Drug Production by Bacteria Uncovered
February 2019 | Science News
Streptozotocin (also known by the trade name Zanosar) is a known antibiotic compound and a drug used to treat metastatic pancreatic islet cell carcinoma. Although a well-known drug, the biosynthetic pathway has remained a black box.
The researchers showed that the compound is produced through an enzymatic pathway and revealed the novel chemistry that drives the process.
Rare stem cell may be the root of all metastatic cancers
February 2019 | Science News
Researchers have made a new discovery about cancer cell metastasis that could completely change treatment approaches in the battle against cancer.
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