Newly discovered hybrid molecules could serve as a novel category of anti-cancer agent
May 2019 | Science News
Researchers have developed and studied the biological activity of five new, metal-organic hybrid knotted molecules, termed metal-organic trefoil knots (M-TKs). These molecules can effectively deliver metals to cancer cells, demonstrating the potential to act as a new category of anti-cancer agents
Alzheimer’s Map Shows Where Epigenetics Takes Wrong Turn
May 2019 | Science News
The new findings center on genetic “volume dials” called enhancers, which turn the activity of genes up or down based on influences such as aging and environmental factors. By taking a comprehensive look at enhancers in brain cells of people at varying stages of Alzheimer’s and comparing them to the cells of healthy people, scientists found that in Alzheimer’s, the loss of epigenetic marks is accelerated.
Capturing Cancer Cells Using a Novel Microfluidic Chip
May 2019 | Science News
To more quickly and efficiently isolate rare circulating tumor cells (CTCs) for analysis, researchers have created a new microfluidic chip that captures nearly every CTC in a sample of blood ¬- more than 99% - a considerably higher percentage than most existing technologies.
Biomarkers to diagnose serious kidney allergic reaction
May 2019 | Science News
Researchers say they have identified two protein biomarkers in urine that may one day be used to better diagnose acute interstitial nephritis (AIN), an underdiagnosed but treatable kidney disorder that impairs renal function in the short term and can lead to chronic kidney disease, permanent damage or renal failure if left unchecked.
Antibody Agents Could Treat Multitude of Blood and Immune Disorders
May 2019 | Science News
An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine.
Different levels of two molecules from same family can influence prognosis of liposarcoma
May 2019 | Science News
Researchers have found that different levels of two molecules of the same family--TIMP-1 and TIMP-4--can influence prognosis of liposarcoma. High levels of TIMP-1 lead to a poor prognosis while high TIMP-4 indicates a less severe form of liposarcoma.
Exploiting a Chink in the Armor of Brain Tumor Cells
May 2019 | Science News
For a long time, researchers have been looking for weaknesses in glioblastoma cells which could be targeted with efficacious therapies. Scientists have found that the expression of a small fatty acid-binding protein (MDGI, or FABP3) in glioblastoma cells increases their ability to invade tissues and is linked with a poorer prognosis for the patient.
Nerve Cell Voltage Finding May Lead to New Therapies for Neurological Disorders
May 2019 | Science News
Researchers say they have discovered that a neuron’s own electrical signal, or voltage, can indicate whether the neuron is functioning normally. If that voltage is absent, scientists say everything is “out of whack.”
The heart 'talks' to fat cells
May 2019 | Science News
Like sending a letter through the mail or a text over a cellular network, the heart can generate messages that travel long distances through the body. Those messages ultimately reach fat cells, new research shows. The findings could have implications for modulating weight gain in patients with heart failure.
Blocking protein-digesting enzyme tricks mice into releasing more beneficial hormones
May 2019 | Science News
Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published.
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.