DNA Circling the Nanopore Drain May Improve Sequencing Flow
August 2019 | Science News
Researchers say defect-guided transport of biomolecules can be of use in a diverse range of technological processes, from lab-on-chip sorting and synthesis of biomolecules to single-molecule nanopore sequencing,
Tiny biodegradable circuits for releasing painkillers inside the body
August 2019 | Science News
Researchers have developed biodegradable microresonators that can be heated locally with a wireless system. Doctors could soon be using them in implants to control the release of painkillers within tissue.
Decoding Pancreatic Cancer’s Invade and Evade Tactics
August 2019 | Science News
Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system. Researchers report the molecular details of this process providing insights into druggable targets for immunotherapies.
Key step toward cancer treatments that leave healthy cells unharmed
August 2019 | Science News
Researchers have opened up a possible avenue for new cancer therapies that don't have the side effects that oftentimes accompany many current cancer treatments by identifying a protein modification that specifically supports proliferation and survival of tumor cells.
AI Identifies New Breast Cancer Subtypes That May Help Personalize Diagnosis and Therapy
August 2019 | Science News
Scientists have used artificial intelligence (AI) and machine learning (ML) to discover five new subtypes of breast cancer that could help clinicians deliver the most effective therapies—including immunotherapy—for individual patients, as well as potentially direct the development of new anticancer drugs.
New Stem Cell Combination Could Help to Repair Damaged Hearts
August 2019 | Science News
Researchers have found that, by transplanting an area of damaged tissue with a combination of both heart muscle cells and supportive cells taken from the outer layer of the heart wall, they may be able to help the organs recover from the damage caused by a heart attack.
Unprecedented Insight into Potential Anticancer Drug Target
August 2019 | Science News
Researchers have now elucidated a structure of the human ASCT2 that provides unprecedented insight in the workings of this protein, and may help the development of drugs. The human glutamine transporter ASCT2 allows the amino acid glutamine to enter cells and is upregulated in many types of cancer cells, which need more glutamine. It is a potential target for new anti-cancer drugs.
Lung Cells Hustle to Repair Damaged DNA Post-influenza Attack
July 2019 | Science News
Scientists have identified one kind of lung cell that can hustle to repair its damaged DNA and survive an attack of the influenza A virus while other kinds of cells around it die in droves.
Gene Therapy Vectors Deliver to More Places Than Once Thought
July 2019 | Science News
Scientist have developed a sensitive screening method for adeno-associated virus (AAV) vectors. Unlike conventional screening methods, which excel at detecting high, stable expression of a reporter gene, the new screening method is designed to capture both high and low transgene expression.
Newly Discovered Role for Alpha-Synuclein Could Point to New Approaches Against Parkinson’s Disease
July 2019 | Science News
A protein found in the characteristic Lewy bodies that form in the brains of patients with Parkinson’s disease (PD), may help to repair double-stranded breaks (DSB) in DNA. Researchers show that the formation of Lewy bodies effectively pulls alpha-synuclein out from the nerve cell nucleus into the cytoplasm. The protein is then prevented from carrying out its normal nuclear role of DNA repair, which leads to increased DSBs, and ultimately the death of brain cells.
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.