Compound Created to Help Reconstruct Myelin in Multiple Sclerosis
September 2019  |  Science News
Researchers have created a compound, that when tested in mice, was able to promote the reconstruction of the myelin sheath surrounding neuronal axons. These findings could pave the way to a new treatment for combating demyelinating conditions such as multiple sclerosis (MS).
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New drug may enhance efficacy of chemotherapy in pancreatic cancer
September 2019  |  Science News
The desmoplastic stroma or the defense wall formed around pancreatic tumor prevents chemotherapy from reaching the tumor. Scientist show using the combination of the peptide and the cytostatics, tumor volume can be drastically reduced in pancreatic cancer.
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Breast Cancer Cells Pushed into Resistant Sleeper Mode by Hormone Therapy
September 2019  |  Science News
Researchers say the findings from studies in laboratory-grown cells could help to identify new strategies for either keeping these dormant cancer cells in perpetual sleeper mode, or potentially kicking them out of dormancy so that they can be killed using existing or new breast cancer therapies.
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The seeds of parkinson's disease: Amyloid fibrils that move through brain
September 2019  |  Science News
Researchers have found that the structure of Parkinson's disease-associated protein aggregates can tell us, for the first time, about their movement through the brain. These new findings indicate that Parkinson's disease is a kind of amyloidosis, which has implications for its diagnosis and treatment.
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Researchers illuminate mysterious aspect of mitochondrial metabolism using a tiny thermometer
August 2019  |  Science News
Researchers say Mitochondria, the cell's power stations, release quick bursts of heat by unleashing the power stored in an internal proton "battery,"
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Human Cortical Organoids Model Neuronal Networks
August 2019  |  Science News
Researchers have shown that organoids derived from human stem cells produce brain waves that become more complex as development progresses. The synchronized neural activity can be blocked by drugs, a sign that cells were communicating with each other and forming functional neural circuits within the miniature brains.
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Novel Method Identifies the Right Individual Exosomes
August 2019  |  Science News
Scientists say new technology will allow large-scale screens for biomarkers in disease, complementing a panel of methods for sensitive and specific detection of exosomes.
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Atherosclerosis Could Be Reversed by Nanoparticle-Encapsulated RNAi Drug
August 2019  |  Science News
Scientists say inhibition of endothelial TGF-β signaling in hyperlipidemic mice reduces vessel wall inflammation and vascular permeability and leads to arrest of disease progression.
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Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy
August 2019  |  Science News
Researchers show that heterogeneity of both breast cancer cells themselves and immune composition of the tumor microenvironment are important considerations for therapy.
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New therapy found to be effective for patients with a particular type of bone marrow cancer
August 2019  |  Science News
Researchers have found a new type of therapy to be effective for patients with a particular type of bone marrow cancer that is resistant to several standard therapies,
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