Novel drug may be the answer in battling resistance in aggressive breast cancer
October 2019  |  Science News
Researchers have discovered the new drug that can save many lives, especially those patients suffering from metastatic or advanced breast cancer. The new drug, known as BOS172722, can block one of cancer’s key evolutionary escape routes from chemotherapy.
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Researchers Identify Pair of "Recruiters" that Pull T Cells to the Lungs
October 2019  |  Science News
scientists found the CD8 T cell receptor CXCR6 and its ligand CXCL16 as necessary for CD8 T cells to reach lung tissue, a process that is particularly critical in cases of lung infection. Epithelial cells lining the airways leading to the lungs produce the ligand CXCL16. The CXCR6 receptor is found on the surface of CD8 T cells, and it streamlines CD8 T cell travel to the lungs.
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Parkinson's disease is also present in the blood
October 2019  |  Science News
The behavior of immune cells in the blood is so different in patients with Parkinson's disease that it advocate for a new type of supplementary medicine, which can regulate the immune system and thus inhibit the deterioration of the brain.
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Culprit for Age-related Decline in Muscle Healing Uncovered
October 2019  |  Science News
An age-related decline in recovery from muscle injury can be traced to a protein that suppresses the special ability of muscle stem cells to build new muscles. Scientist figured out that a protein called GAS1 is the culprit for this age-related decline.
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New Potential Early Stage Treatment for Parkinson's
September 2019  |  Science News
Researchers have identified a molecular defect common to all people with the condition that may help pave the way for early diagnosis and new treatment options.
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Healthy neurons form surprising connections with aggressive brain cancer cells
September 2019  |  Science News
Research shows that impulses from neurons are transmitted to cancer cells through synapses and transformed into signals in cancer cells that stimulate growth, giving a new hope of for brain cancer treatment with anti-epileptic medicine.
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Cancer Immunotherapy Resistance Due to Metabolic Imbalance
September 2019  |  Science News
Researchers have discovered that a metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drugs is associated with resistance to the immunotherapy agent and shorter survival.
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Mystery underlying heart toxicity caused by diabetes drugs solved
September 2019  |  Science News
New diabetes medications, aims to tackle two major complications of diabetes -- the excess of both lipids and glucose in the blood -- the therapeutic benefits, while great, frequently are accompanied by dangerous toxic effects to the heart.
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Switch That Kills Inactive HIV Identified
September 2019  |  Science News
Researchers have identified a principal cellular player controlling HIV reproduction in immune cells which, when turned off or deleted, eliminates dormant HIV reservoirs.
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Cellular senescence is associated with age-related blood clots
September 2019  |  Science News
Researchers have identified 44 specific senescence-associated proteins that are involved in blood clotting, marking the first time that cellular senescence has been associated with age-related blood clots.
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