New Treatment Reverses Signs of Brain Aging in Mice
December 2020 | Science News
A small molecule drug known as integrated stress response inhibitor (ISRIB) in aged mice indicate that ISRIB may be key to treating age-related cognitive decline.
Drug Targets Cold Tumors' Achilles Heel
December 2020 | Science News
Researchers identified that a cellular protein known as SerpinB9, or Sb9, could represent cold tumors’ Achilles heel. The expression of Sb9 in mouse models of cancer showed that this protein protects tumors from immunological attack.
New insulin molecule can self-regulate blood sugar in rats
December 2020 | Science News
Researchers have developed a novel insulin molecule that responds to glucose levels in the blood sugar of rats, which they say could help patients with type 1 diabetes.
Oral drug blocks SARS-CoV-2 transmission
December 2020 | Science News
Researchers have discovered possible treatment of SARS-CoV-2 infection with a new antiviral drug, MK-4482/EIDD-2801 or Molnupiravir, completely suppresses virus transmission within 24 hours.
Steering Stem Cells to Repair Sites Using Inflammo-Free Inflammo-Attraction
November 2020 | Science News
Scientists say a natural inflammo-attraction system guides stem cells to inflammatory signals emitted by damaged tissue. They reported their group modified an inflammatory “homing” molecule to create a drug that enhances stem cell binding and minimizes inflammatory signaling.
Coronavirus Proteins Move, Change Shape and Vibrate To Get in Our Cells
November 2020 | Science News
Researchers say that the vibrations of the protein spikes on coronaviruses, including the one that causes Covid-19, play a crucial part in allowing the virus to penetrate human cells.
The proteasome presents an interesting but complex target for anti-cancer therapeutics.
November 2020 | Science News
Targeting PSMD14 would allow scientists to selectively target the proteasome without inducing catastrophic dysfunction,
The Enzyme That Keeps Viruses In Stealth Mode
November 2020 | Science News
Researchers found an enzyme called sphingosine kinase 2, or SphK2, that allows viruses to remain in stealth mode, evading immune clearance.
Researchers develop ACE2 decoy to neutralise SARS-CoV-2
November 2020 | Science News
Using their de novo protein design strategy, researchers engineered human angiotensin converting enzyme 2 (hACE2) protein decoys that can protect cells from SARS-CoV-2 infection.
A viable vaccine for tough tumors
November 2020 | Science News
Biomaterial-based cancer vaccine combines chemo and immunotherapy to treat triple-negative breast cancer in mice
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.