The ever-changing brain: Shining a light on synaptic plasticity
November 2019 | Science News
Researchers have found that AMPA receptors form and disintegrate continually, within a fraction of a second, rather than existing as stable entities. The scientists' findings may help clarify early stages of synaptic plasticity: neural activity that is key for learning and memory.
Researchers develop method to isolate T cells primed for certain allergies or infections
November 2019 | Science News
Researchers have now devised a way to identify T cells that share a particular target, as part of a process called high-throughput single-cell RNA sequencing. This kind of profiling can reveal the unique functions of those T cells by determining which genes they turn on at a given time. In a new study, the researchers used this technique to identify T cells that produce the inflammation seen in patients with peanut allergies.
Cell Therapy Aims To Improve Memory and Prevent Seizures Following Traumatic Brain Injury
November 2019 | Science News
Researchers developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury.
Master regulator in mitochondria is critical for muscle function and repair
November 2019 | Science News
Scientists identified how MICU1, a protein in the mitochondria, the "powerhouses" of all cells, is critical in the maintenance of muscle size and function, and the repair of damaged muscle fibers.
Novel Fluorescence Lifetime Imaging Tool May Advance Cancer Care
November 2019 | Science News
Scientists described and demonstrated a new technique for fluorescence lifetime imaging of tissue and cells in a fast and comprehensive manner, thus laying the groundwork for use in a clinical setting. They believe that FLI-Net is well suited to accurately quantify complex fluorescence lifetimes in cells and, in real time, in intact animals without any parameter settings.
Leukemia type B cell can transform into a macrophage through epigenetic changes
November 2019 | Science News
Scientists obtained a high-resolution epigenetic profile of each step of the transdifferentiation process by using a cellular model of lymphoblastic leukemia B cells that they transformed into macrophages.
Protein could offer therapeutic target for pancreatic cancer
November 2019 | Science News
A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified.
CRISPR Gene Editing Ability Improved by Specific Modifications of tracrRNA
November 2019 | Science News
Scientists believe they may have found a way to sharpen the fastest, cheapest, and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.
Stem cell transplants used to grow fully functional lungs in mice
November 2019 | Science News
Researchers were able to grow fully functional lungs in mouse embryos using transplanted stem cells. The findings suggest that it may be ultimately possible to use the technique to grow human lungs in animals for patients who need transplants and to study new lung treatments.
Researchers reveal mechanisms that lead to onset of Type 1 diabetes
November 2019 | Science News
Scientists have mapped out the switches that activate genes responding to an inflammatory environment in the pancreatic islets, it will be much easier to test different hypotheses of how common genetic variants are affecting the islet cells in T1D.
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.