Protein Proffers Exercise Health Gains, without the Pain
January 2020 | Science News
Researchers have found that a conserved class of proteins known as Sestrins can mimic many of the beneficial effects of exercise on metabolism in flies and mice, and boost their physical endurance.
Researchers visualize molecular organization of TNFα receptor molecules
January 2020 | Science News
Researchers have visualized the molecular organization of individual TNFα receptor molecules and the binding of TNFα to the cell membrane in cells using optical microscopy.
Exosome Therapy for Stroke Produces Full Recovery in Animal Model
January 2020 | Science News
Researchers report the first observational evidence during a midline shift—when the brain is being pushed to one side—to suggest that a minimally invasive and nonoperative exosome treatment can now influence the repair and damage that follow a severe stroke.
Pinpointing Diabetes Prevention Using Proteomics
January 2020 | Science News
Research team used a new strategy to pinpoint proteins in beta cells, a subset of pancreatic islets that increase or decrease in response to immune system attack.
Disrupting Leukemia's Deadly Reliance on Vitamin B6
January 2020 | Science News
A team of researchers may have found a way to stop the growth of AML; the cancer relies on vitamin B6 to survive, so preventing B6 from aiding in the creation of new cells may be a way to halt the cancer without hurting healthy cells.
Islet protective factor GDF15 reduces development of type 1 diabetes in mice
January 2020 | Science News
Researchers have discovered that type 1 diabetes patients have low levels of growth differentiation factor 15 (GDF15) in their pancreatic β cells, unlocking a potential alternative to life-long type 1 diabetes disease management.
New function for potential tumor suppressor in brain development
January 2020 | Science News
Researchers have uncovered a novel, opposite role for Cdkn1c. When Cdkn1c is removed only in certain cells of the brain, these cells die, arguing for a new growth promoting role of Cdkn1c.
Pancreatic cancer cells release signal to suppress immune system's attack on tumors
January 2020 | Science News
Study shows an immune signaling protein, interleukin-1β (IL-1β), is made and released by pancreatic tumor cells to reduce anti-cancer immune responses, which promoted the growth of pancreatic ductal adenocarcinoma or PDA, a form of cancer that is usually deadly within two years.
"Good" T Cells Can Go "Bad," But in the Case of Cancer, That's A Good Thing
January 2020 | Science News
Researchers identified T cell growth factor interleukin (IL)-2 and transcription factor Blimp-1 as factors responsible for altering CD4+ T cells’ functional identity, triggering the change from regulatory to cytotoxic in the context of cancer.
RNA-targeting strategy can block Parkinson’s disease driver
January 2020 | Science News
A new drug-like compound has been developed which reportedly prevents the body from producing a protein that’s often at the root of Parkinson’s disease.
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.