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Molecular 'switch' reverses chronic inflammation and aging
February 2020  |  Science News
Overactivation of the NLRP3 inflammasome has been linked to a variety of chronic conditions, including multiple sclerosis, cancer, diabetes and dementia.
Read the Full Article from ScienceDaily
HIV Viral Structures Improve Therapeutics
February 2020  |  Science News
The intasome is a critical part of the HIV structure of which enables infection by integrating the virus’s genetic material into human DNA. This is why some drugs, called integrase strand transfer inhibitors (INSTIs), treat HIV by blocking the actions of intasome.
Read the Full Article from Labroots
Glioblastoma Alters Synaptic Function to Promote Tumor Growth
January 2020  |  Science News
Researchers indicate that glioblastoma brain tumors impact on the activity of neighboring neurons, promoting a vicious cycle that alters gene expression . They showed that variants of the PIK3CA gene promote tumor progression, and that two variants in particular altered the expression of genes involved in synaptic function.
Read the Full Article from GEN
Cardiac Cell Therapy: Dead or Alive?
January 2020  |  Science News
New study suggests the benefits of adult stem cell therapies are directly due to a modified immune response, showing modest improvement in heart function.
Read the Full Article from GEN
Small molecule targeting mRNA could slow the progression of Parkinson’s disease
January 2020  |  Science News
Researchers are developing a small molecule that targets the messenger RNA (mRNA) of α-synuclein, preventing the formation of the misfolded protein and halting the progression of Parkinson’s disease.
Read the Full Article from DrugTargetReview
New Model Simulates Accumulation of Lipids in Membranes
January 2020  |  Science News
Cholesterol may be responsible for destabilizing the membranes and helping nanometric-sized objects to enter the cells.
Read the Full Article from Technologynetworks
Natural Body Protein Found to Suppress Breast Cancer Metastasis
January 2020  |  Science News
According to the research study, A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors.
Read the Full Article from GEN
Techniques to disrupt HIV viral latency could help a future cure
January 2020  |  Science News
Research says two possible therapeutic approaches to cause dormant HIV to re-emerge from their latency reservoir could provide new possible avenues to a cure for HIV.
Read the Full Article from DrugTargetReview
Huntington's Protein Has Unexpected Roles in Body Movement and Aging
January 2020  |  Science News
Researchers have discovered that neurons in the striatum, a brain area involved in controlling movement, require the huntingtin gene for regulating the body’s movements, maintaining cell health during aging, and developing functioning connections between cells.
Read the Full Article from Technologynetworks
Epigenetic Changes Make Breast Cancer Cells Drug Resistant
January 2020  |  Science News
scientists have found that in ER+ breast cancer cells that resist treatment, the genome has been structurally rewired. This 3D change alters which genes are active or inactive.
Read the Full Article from Labroots

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