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Master regulator in mitochondria is critical for muscle function and repair
November 2019  |  Science News
Scientists identified how MICU1, a protein in the mitochondria, the "powerhouses" of all cells, is critical in the maintenance of muscle size and function, and the repair of damaged muscle fibers.
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Novel Fluorescence Lifetime Imaging Tool May Advance Cancer Care
November 2019  |  Science News
Scientists described and demonstrated a new technique for fluorescence lifetime imaging of tissue and cells in a fast and comprehensive manner, thus laying the groundwork for use in a clinical setting. They believe that FLI-Net is well suited to accurately quantify complex fluorescence lifetimes in cells and, in real time, in intact animals without any parameter settings.
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Leukemia type B cell can transform into a macrophage through epigenetic changes
November 2019  |  Science News
Scientists obtained a high-resolution epigenetic profile of each step of the transdifferentiation process by using a cellular model of lymphoblastic leukemia B cells that they transformed into macrophages.
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Protein could offer therapeutic target for pancreatic cancer
November 2019  |  Science News
A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified.
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CRISPR Gene Editing Ability Improved by Specific Modifications of tracrRNA
November 2019  |  Science News
Scientists believe they may have found a way to sharpen the fastest, cheapest, and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.
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Stem cell transplants used to grow fully functional lungs in mice
November 2019  |  Science News
Researchers were able to grow fully functional lungs in mouse embryos using transplanted stem cells. The findings suggest that it may be ultimately possible to use the technique to grow human lungs in animals for patients who need transplants and to study new lung treatments.
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Researchers reveal mechanisms that lead to onset of Type 1 diabetes
November 2019  |  Science News
Scientists have mapped out the switches that activate genes responding to an inflammatory environment in the pancreatic islets, it will be much easier to test different hypotheses of how common genetic variants are affecting the islet cells in T1D.
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APOE Mutation Linked to Protection From Alzheimer’s: Case Study
November 2019  |  Science News
Researchers have identified an APOE genetic mutation that may help mitigate the risk of some forms of Alzheimer’s. The team showed using in vitro experiments that the sequence, known in the scientific literature as the Christchurch variant, stops the protein product of the gene from binding strongly to its usual targets—sugar molecules involved in the accumulation of tau and neuron damage—and could thus have had a protective effect.
Read the Full Article from TheScientist
AI Blood Test Can Spot Signs of Brain Tumour To Speed Up Diagnosis
November 2019  |  Science News
Chemical analysis of blood samples, combined with an artificial intelligence program, could speed up the diagnosis of brain tumours according to research presented at the 2019 NCRI Cancer Conference.
Read the Full Article from Technolgynetworks
Discovery of 'cellular bike couriers' could shed light on disease spreading mechanisms
October 2019  |  Science News
The new vesicle discovered by scientists is the first to be identified in twenty years and is the smallest known.
Read the Full Article from NewsMedicalLifeScience