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Using blue light to control CAR T cells and destroy tumours
February 2020  |  Science News
Researchers have created a method to activate CAR T cells with blue LED light to successfully combat solid tumors in mice.
Read the Full Article from DrugTargetReview
What We Know Today about Coronavirus SARS-CoV-2 and Where Do We Go from Here
February 2020  |  Science News
The sequence of the SARS-CoV-2 genome has enabled the development of polymerase chain reaction (PCR) based diagnostics that can be brought to the front lines and leveraged for rapid identification of infected individuals.
Read the Full Article from GEN
Coronavirus Antiviral Drug Discovery
February 2020  |  Science News
The drug remdesivir (RDV) is a nucleoside analog that inhibits the coronavirus RNA-dependent RNA polymerase (RDRP). Remdesivir activity has not been tested against nCoV2019, but nCoV2019 similarity to other viruses is promising.
Read the Full Article from American Society of Microbiology
Researchers develop screening platform to detect new antibiotics
February 2020  |  Science News
Scientists designed a system that would test antibiotics to target a small RNA region in the ribosome, called the peptidyl transferase centre (PTC).
Read the Full Article from DrugTargetReview
High Testosterone in Women Linked to Type 2 Diabetes
February 2020  |  Science News
Having genetically higher testosterone levels increases the risk of metabolic diseases such as type 2 diabetes in women, while reducing the risk in men. Higher testosterone levels also increase the risks of breast and endometrial cancers in women, and prostate cancer in men.
Read the Full Article from Technologynetworks
Blocking Problem Protein Shows Promise for Preventing Heart Attacks
February 2020  |  Science News
New research has shown that a protein called Plexin D1, that detects disturbances in blood flow caused by damage to arteries, plays a key role in the formation of these atherosclerosis plaques.
Read the Full Article from Labroots
Cancer-fighting compound reduces fat in obese mice
February 2020  |  Science News
Scientist reported that G-1, a cancer-fighting compound, reduces fat in obese mice. The weight loss wasn't due to the mice eating less or moving around more; it resulted from what their bodies did with the calories they ate. Instead of storing calories as fat, the mice used them as fuel.
Read the Full Article from NewsMedicalLifeScience
Molecular 'switch' reverses chronic inflammation and aging
February 2020  |  Science News
Overactivation of the NLRP3 inflammasome has been linked to a variety of chronic conditions, including multiple sclerosis, cancer, diabetes and dementia.
Read the Full Article from ScienceDaily
HIV Viral Structures Improve Therapeutics
February 2020  |  Science News
The intasome is a critical part of the HIV structure of which enables infection by integrating the virus’s genetic material into human DNA. This is why some drugs, called integrase strand transfer inhibitors (INSTIs), treat HIV by blocking the actions of intasome.
Read the Full Article from Labroots
Glioblastoma Alters Synaptic Function to Promote Tumor Growth
January 2020  |  Science News
Researchers indicate that glioblastoma brain tumors impact on the activity of neighboring neurons, promoting a vicious cycle that alters gene expression . They showed that variants of the PIK3CA gene promote tumor progression, and that two variants in particular altered the expression of genes involved in synaptic function.
Read the Full Article from GEN