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The most sensitive Methyltransferase Activity Assay Kits

September 2017  |  Press Releases

The most sensitive Methyltransferase Activity Assay Kits


MILPITAS, Calif. - Sept. 23, 2016 - PRLog -- Methyltransferases are a diverse group of enzymes that methylate proteins, DNA, and small molecule targets. Accordingly, methyl transferase activity plays a critical role in modulating gene transcription, protein interactions, and signaling networks. BioVision is excited to introduce two Methyltransferase Activity Assay Kits (Colorimetric & Fluorometric) that allow for kinetic evaluation ofmethyltransferase activity of purified enzymes and their inhibitors. Methyltransferase activity is detected by coupling the methyl transfer reaction to a multi-step enzymatic cascade. These kits are highly sensitive, ready-to-use and can detect Methyltransferase activities as low as 10 µU/ml of purified enzymes.
Key Features:
• Non-radioactive
• Specific, homogeneous assays
• Versatile: colorimetric and fluorometric formats
• Convenient: minimal sample preparation, fast protocols (1-2 hours)
• Cost-effective: 100 assays
• Adaptable: works with most of the commonly available instrumentations
Figure-A. Representative activity curve for human recombinant Nicotinamide N-Methyltransferase (NNMT) using K986-100 at 37°C. Figure-B. representative activity curve for human recombinant Protein Arginine Methyltransferase 1 (hPRMT1) with Histone H4 Substrate using K521-100 at 25°C.
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About BioVision:

BioVision, Inc. is a privately held Life Science company headquartered in the beautiful San Francisco Bay area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, and more.

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