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PicoProbe™ Methylglyoxal Assay Kit (Fluorometric) (K461-100)

July 2018

PicoProbe™ Methylglyoxal Assay Kit (Fluorometric) (K461-100)

FOR IMMEDIATE RELEASE

MILPITAS, Calif. - July 18, 2018 - PRLog -- Methylglyoxal (MG, 2-oxopropanal, pyruvic aldehyde), a by-product of glycolysis, is a highly toxic, reactive dicarbonyl compound. It causes non-enzymatic glycation of proteins which yields irreversible advanced glycation end products (AGEs), leading to cross-linking or degradation of proteins. MG is associated with several pathologies including diabetes, aging and neurodegenerative diseases. Furthermore, recent studies have suggested that MG may induce carbonyl stress-type schizophrenia. BioVision's PicoProbeTMMethylglyoxal Assay Kit (Fluorometric) can detect MG using an enzyme-coupled reaction which reduces the fluorogenic probe. The reduced fluorophore produces a stable signal (Ex/Em= 535/587nm), which is directly proportional to the amount of MG in samples. The assay is simple, reproducible and can specifically detect as low as 6 pmol of MG in a 100 µl reaction.


Figure:Measurement of Methylglyoxal (K461-100) in Mouse Liver (4 mg tissue), Rat Brain (12 mg tissue) and Human Cerebrospinal Fluid (CSF, 2 µl). All assays were performed following kit protocol.

For complete information on this assay kit, visit: https://www.biovision.com/picoprobetm-methylglyoxal-assay...

About BioVision:
BioVision, Inc. is a privately held Life Science company headquartered in the beautiful San Francisco Bay area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, and more.


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