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Lithium Assay Kit: Small Atom, Big Applications

October 2017

Lithium Assay Kit: Small Atom, Big Applications


MILPITAS, Calif. - Oct. 26, 2017 - PRLog -- Lithium, the lightest alkali metal, is not considered to be an essential human dietary nutrient. However, lithium has medicinal uses: it is used to treat bipolar depression and mania. Lithium is the simplest possible drug and, cannot be metabolized by the body. Lithium has a defined therapeutic/toxic ratio and requires continuous monitoring (Accepted [Li] in serum: 0.6-1.2 mM; Fatal if [Li] > 1.5 mM). BioVision is proud to introduce the first Lithium Assay Kit that allows for quantification of lithium in serum and plasma. This assay is quick, high-throughput adaptable, and specific with no interference from other ions such as Sodium, Magnesium, Calcium, Cobalt, Copper, Zinc, and Iron).

Estimation of Lithium in human serum

Key Features:

• Non-radioactive
• Specific, homogeneous assay
• Convenient: minimal sample preparation; fast protocols (1-2 hours )
• Cost effective: 100 assays; High Throughput Screening compatible
• Validated: serum, plasma

Figures. (A) Estimation of lithium in human serum. Normal "off-the-clot" pooled serum was spiked with Lithium standard. Recovery rates: 100.3 – 105.5%. Potential interference by excessive serum sodium: Serum sample was spiked with 40 mM NaCl (hypernatremia)Interference was equivalent to ≤10%). (B) Specificity for detection of Lithium (Li+) over other common monovalent, divalent and trivalent ions. Interference by tested cations: ≤10%.

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About BioVision:

BioVision, Inc. is a privately held Life Science company headquartered in the beautiful San Francisco Bay area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, and more.

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