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FAAH1 Inhibitor Screening Kit (Fluorometric)

September 2019

FAAH1 Inhibitor Screening Kit (Fluorometric)

It is simple, sensitive, Rapid and Reliable test suitable for high-throughput screening of Fatty Acid Amide Hydrolase inhibitors.

FOR IMMEDIATE RELEASE

MILPITAS, Calif. - Sept. 23, 2019 - PRLog -- Fatty Acid Amide Hydrolase (FAAH; EC: 3.5.1.99), also known as Oleamide Hydrolase or Anandamide Amidohydrolase is a member of the serine hydrolase family of enzymes. It is an integral membrane enzyme that hydrolyzes the endocannabinoid anandamide and related amidated signaling lipids. Endocannabinoids are endogenous lipid ligands that activate the Cannabinoid G-protein coupled Receptors (CB). CB1 and CB2 modulate physiological and behavioral processes such as pain, anti-inflammation etc. In addition to hydrolyzing Endocannabinoids, FAAH regulates other lipid signaling molecules with anti-inflammatory and analgesic properties. Recent study suggests that FAAH may represent an attractive therapeutic target for treatment of pain, inflammation etc. In BioVision's Human FAAH1 Inhibitor Screening Kit, FAAH1 hydrolyzes a non-fluorescent substrate to generate a fluorescent product, 7-amino-4-methylcoumarin, which can be measured at Ex/Em = 360/465 nm. In the presence of FAAH1 Inhibitor, the reaction is impeded. The assay is highthroughput adaptable and can be completed in less than 1 hr.

Figure: Inhibition of Human FAAH1 activity by FAAH1 Inhibitor (IC50 = 6.6 nM).

For more information on this kit please visit https://www.biovision.com/faah1-inhibitor-screening-kit-fluorometric.html

About BioVision:
BioVision, Inc. is a privately held Life Science company headquartered in the beautiful San Francisco Bay area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, and more.


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