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BioVision is proud to launch DNAse-I Activity Fluorometric Assay Kit

March 2017
BioVision is proud to launch DNAse-I Activity Fluorometric Assay Kit

BioVision is proud to launch DNAse-I Activity Fluorometric Assay Kit


MILPITAS, Calif. - March 6, 2017 - PRLog -- Deoxyribonuclease I (DNAse I) is an endonuclease that cleaves DNA phosphodiester bonds. DNAse I targets single-stranded DNA, double-stranded DNA, and chromatin in a non-specific manner.  Abnormal DNAse I activity occurs in association with a variety of cancers and auto-immune diseases that exhibit elevated levels of cell-free DNA. BioVision's DNAse I Activity Fluorometric Assay Kit allows for quantitative evaluation of DNAse I activity of purified enzymes and their inhibitors as well as comparative examination of DNAse I activity in biological samples. Enzyme activity is directly detected upon cleavage of a DNA Probe, which yields a fluorescent DNA product. Our assay kit is simple (does not require antibodies or PCR tools), sensitive, specific and validated with human serum.
Key Features:
• Simple: Direct measurement of DNAse (Enzyme-based principle)
• Non-radioactive
• Specific, homogeneous assays
• Accurate: reproducible results
• Convenient: minimal sample preparation; fast protocols (1-2 hours )
• Cost effective: 100 assays; High Throughput Screening compatible
• High-Throughput Compatible

Figure: (A) Representative activity curves for purified DNAse I (orange), serum sample (green), and background control (blue) at 37°C; B) comparative analysis of DNAse I activity from 25 µl undiluted single donor normal vs. Systematic Lupus Erythematosus (SLE) patient serum sample.

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About BioVision:

BioVision, Inc. is a privately held Life Science company headquartered in the beautiful San Francisco Bay area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, and more.

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