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Nek2/Hec1 inhibitor

An inhibitor of Nek2/Hec1
Catalog #: B2924
SKU-Size Size Price Qty
B2924-5 5 mg
$125.00
B2924-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide; N-[4-(2,4-Dimethylphenyl)thiazol-2-yl]isonicotinamide
Appearance Solid
CAS # 560103-80-2
Molecular Formula C₁₇H₁₅N₃OS
Molecular Weight 309.39
Purity 97%
Solubility Soluble in in DMSO
SMILES O=C(C1=CC=NC=C1)NC2=NC(C3=CC=C(C)C=C3C)=CS2
InChi InChI=1S/C17H15N3OS/c1-11-3-4-14(12(2)9-11)15-10-22-17(19-15)20-16(21)13-5-7-18-8-6-13/h3-10H,1-2H3,(H,19,20,21)
InChi Key IBQLKKBLBXJSGU-UHFFFAOYSA-N
PubChem CID 4363180
MDL Number MFCD03384899
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Nek2/Hec1 inhibitor targets the Hec1/Nek2 pathway and causes chromosome mis-alignment as well as cell death. The IC₅₀ for cytotoxicity in MDA-MB231, MDA-MB468, HeLa and K562 cell lines is 1.1 μM, 3.4 μM,1.6 μM and 1.2 μM respectively.


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