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A protein implicated in cell cycle progression and cytoskeletal regulation
Catalog #: 4843

Product Details

Cat # +Size 4843-25
Size 25 μg
Alternate Name NEDD8-Aminomethylcoumarin
Appearance Liquid
Physical Form Description A solution in DMSO ( 1 mg/ml)
Molecular Weight 8.735 kDa
Purity by ≥95%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans


Prepared by the C-terminal derivatisation of NEDD8 with 7-amino-4-methylcoumarin. NEDD8-AMC acts as a useful and sensitive fluorogenic substrate for deNEDDylating enzymes, including NEDP1 and UCH-L3. It is a useful reagent for the study of deNEDDylating activity where detection sensitivity or continuous monitoring of activity is essential.

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