Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A necroptosis inhibitor
Catalog #: 1864
SKU-Size Size Price Qty
1864-5 5 mg
1864-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; Methylthiohydantoin-DL-tryptophan; Nec-1
Appearance Yellow solid
CAS # 4311-88-0
Molecular Formula C₁₃H₁₃N₃OS
Molecular Weight 259.33
Purity ≥98% by TLC
Solubility DMSO (~25 mg/ml) or EtOH (~ 6 mg/ml)
InChi InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)
PubChem CID 2828334
MDL Number MFCD00056916
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC₅₀ = 180 nM).

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.