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NCGC00244536

A potent KDM4A inhibitor
Catalog #: B1956

In stock

SKU-Size Size Price Qty
B1956-5 5 mg
$125.00
B1956-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 3-(8-hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide
Appearance Crystalline solid
CAS # 2003260-55-5
Molecular Formula C₂₅H₂₂N₂O₂
Molecular Weight 382.46
Purity ≥98% by HPLC
Solubility DMSO
SMILES C1=CC=C(C=C1)CCCNC(=O)C2=CC=CC(=C2)C3=CC(=C4C(=C3)C=CC=N4)O
InChi InChI=1S/C25H22N2O2/c28-23-17-22(16-20-12-6-13-26-24(20)23)19-10-4-11-21(15-19)25(29)27-14-5-9-18-7-2-1-3-8-18/h1-4,6-8,10-13,15-17,28H,5,9,14H2,(H,27,29)
InChi Key NYKBXXGHEMXSBB-UHFFFAOYSA-N
PubChem CID 127030711
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

NCGC00244536 is a potent KDM4A inhibitor (IC₅₀ = 10 nM). NCGC00244536 displays high selectivity for the fast-growing AR-negative PC3 cells (IC₅₀ = 40 nM) and over 100-fold selectivity against the immortalized prostate epithelial cell lines PrEC1 and PrEC4. Displays anticancer activity.


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