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Naringenin

An antioxidant and an ACAT inhibitor
Catalog #: 1772
SKU-Size Size Price Qty
1772-250 250 mg
$50.00
1772-1000 1 g
$155.00
More Sizes Get Quote

Product Details

Alternate Name 5,7,4'-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; NGEN
Appearance Brown solid
CAS # 480-41-1
Molecular Formula C₁₅H₁₂O₅
Molecular Weight 272.26
Purity ≥98% by TLC
Solubility DMSO or EtOH (50 mg/ml)
SMILES C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
InChi InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
InChi Key FTVWIRXFELQLPI-UHFFFAOYSA-N
PubChem CID 932
MDL Number MFCD00006844
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The major flavanone found in grapefruit. Acts as an antioxidant, free radical scavenger and carbohydrate metabolism promoter. Shows cytotoxicity in various human cell lines and promotes apoptosis in rat C6 glioma model. Naringenin seems to protect LDL-receptor deficient mice from the obesity effects of a high-fat diet. Also lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed with a high-cholesterol diet.


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