Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

α-naphthoflavone

A potent inhibitor of Cytochrome P450 enzymes (Aromatase, 1A2, 1A1, 1B1)
Catalog #: 2918
SKU-Size Size Price Qty
2918-5 5 g
$85.00
2918-25 25 g
$295.00
More Sizes Get Quote

Product Details

Alternate Name 2-phenyl-4H-naphtho[1,2-b]pyran-4-one, NSC 407011, 7,8-Benzoflavone
Appearance Crystalline solid
CAS # 604-59-1
Molecular Formula C₁₉H₁₂O₂
Molecular Weight 272.3
Purity ≥98%
Solubility DMSO (~10 mg/ml) or DMF (~20 mg/ml), Ethanol (~1 mg/ml)
SMILES O=C1C2=C(C(C=CC=C3)=C3C=C2)OC(C4=CC=CC=C4)=C1
InChi InChI=1S/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H
InChi Key VFMMPHCGEFXGIP-UHFFFAOYSA-N
PubChem CID 11790
MDL Number MFCD00004985
Handling Protect from air, light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Potent and selective inhibitor of CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50 = 500, 60, 6, and 5 nM respectively). Can activate CYP3A4 (Kd = 7.4 µM).


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.