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A potent and selective NAMPT (Nicotinamide phosphoribosyltransferase) inhibitor
Catalog #: B1171
SKU-Size Size Price Qty
B1171-5 5 mg
B1171-25 25 mg
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Product Details

Alternate Name 2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide
Appearance Crystalline solid
CAS # 1698878-14-6
Molecular Formula C₂₀H₂₅N₃O₅S
Molecular Weight 419.49
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C20H25N3O5S/c1-20(2,25)14-29(26,27)22-17-6-5-16-12-23(9-7-15(16)10-17)19(24)13-28-18-4-3-8-21-11-18/h3-6,8,10-11,22,25H,7,9,12-14H2,1-2H3
PubChem CID 92044379
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Nampt-IN-1 is a potent and selective NAMPT (Nicotinamide phosphoribosyltransferase) inhibitor. Displays potent anticancer properties. NAMPT is found to be upregulated in various cancer cells and inhibition of NAMPT leads to depletion of NAD+ which leads to low levels of ATP resulting in attenuation of proliferating cancer cells.

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