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Nafamostat Mesylate

A broad spectrum serine protease inhibitor
Catalog #: 1760
SKU-Size Size Price Qty
1760-10 10 mg
$80.00
1760-50 50 mg
$280.00
More Sizes Get Quote

Product Details

Alternate Name 4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate; FUT-175; Futhan
Appearance Off-white solid
CAS # 82956-11-4
Molecular Formula C₁₉H₁₇N₅O₂.2CH₄O₃S
Molecular Weight 539.59
Purity ≥97% by HPLC
Solubility DMSO (100 mM) and H₂O (100 mM)
SMILES CS(=O)(=O)O.CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N
InChi InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;2*1-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);2*1H3,(H,2,3,4)
InChi Key SRXKIZXIRHMPFW-UHFFFAOYSA-N
PubChem CID 5311180
MDL Number MFCD00941430
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A broad-spectrum, synthetic serine protease inhibitor and an inhibitor of the classical and alternative ways of complement activation. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma.


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