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Myeloperoxidase Inhibitor

A potent myeloperoxidase (MPO) inhibitor
Catalog #: 1977
SKU-Size Size Price Qty
1977-100 100 mg
$60.00
1977-500 500 mg
$175.00
More Sizes Get Quote

Product Details

Alternate Name 4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
Appearance White to off-white solid
CAS # 5351-17-7
Molecular Formula C₇H9N₃O
Molecular Weight 151.17
Purity ≥95% by HPLC
Solubility DMSO
SMILES C1=CC(=CC=C1C(=O)NN)N
InChi InChI=1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)
InChi Key WPBZMCGPFHZRHJ-UHFFFAOYSA-N
PubChem CID 21450
MDL Number MFCD00007606
Handling Protect from light and mositure
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC₅₀ = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H₂O₂-induced apoptosis in HL-60, human leukemia cells.


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