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MX1013

A dipeptide caspase inhibitor
Catalog #: B2588
SKU-Size Size Price Qty
B2588-5 5 mg
$125.00
B2588-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name MX-1013, Z-VAL-DL-ASP-FLUOROMETHYLKETONE, MX 1013, 3-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)-5-fluoro-4-oxopentanoic acid, Z-VD-FMK
Peptide Sequence Z-VD-FMK
Appearance Lyophilized solid
CAS # 582316-00-5
Molecular Formula C₁₈H₂₃FN₂O₆
Molecular Weight 382.39
Purity ≥95% by HPLC
Solubility in DMSO
SMILES CC(C)C(C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1
InChi InChI=1S/C18H23FN2O6/c1-11(2)16(17(25)20-13(8-15(23)24)14(22)9-19)21-18(26)27-10-12-6-4-3-5-7-12/h3-7,11,13,16H,8-10H2, 1-2H3,(H,20,25)(H,21,26)(H,23,24)/t13?,16-/m0/s1
InChi Key LYBWGROBJJXCJJ-VYIIXAMBSA-N
PubChem CID 9821317
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

MX-1013, as a potent, irreversible dipeptide caspase inhibitor. It inhibits caspases 1, 3, 6, 7, 8, and 9, with IC₅₀ values ranging from 5 to 20 nm. MX1013 is selective for caspases, and is a poor inhibitor of non-caspase proteases, such as cathepsin B, calpain I, or Factor Xa (IC₅₀ values >10 µM).


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