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A dual inhibitor of EGFR and PI3K
Catalog #: B1968
SKU-Size Size Price Qty
B1968-5 5 mg
B1968-25 25 mg
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Product Details

Alternate Name N-[2-chloro-5-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]pyridin-3-yl]methanesulfonamide
Appearance Crystalline solid
CAS # 1952236-05-3
Molecular Formula C₂₀H₁₄Cl₂FN₅O₂S
Molecular Weight 478.33
Purity ≥98% by HPLC
Solubility DMSO
SMILES CS(=O)(=O)NC1=C(N=CC(=C1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)Cl
InChi InChI=1S/C20H14Cl2FN5O2S/c1-31(29,30)28-18-7-12(9-24-19(18)22)11-2-5-17-14(6-11)20(26-10-25-17)27-13-3-4-16(23)15(21)8-13/h2-10,28H,1H3,(H,25,26,27)
PubChem CID 121416213
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


MTX-211 is a dual inhibitor of EGFR and PI3K. Potentially useful for treatment of KRAS mutant colorectal cancer.

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