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MS436

A potent BRD4 bromodomain inhibitor
Catalog #: 2680
SKU-Size Size Price Qty
2680-5 5 mg
$115.00
2680-25 25 mg
$460.00
More Sizes Get Quote

Product Details

Alternate Name (E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide
Appearance Red solid
CAS # 1395084-25-9
Molecular Formula C₁₈H₁₇N₅O₃S
Molecular Weight 383.42
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES CC1=CC(=NNC2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=N3)C(=CC1=O)N
InChi nChI=1S/C18H17N5O3S/c1-12-10-16(15(19)11-17(12)24)22-21-13-5-7-14(8-6-13)27(25,26)23-18-4-2-3-9-20-18/h2-11,21H,19H2,1H3,(H,20,23)/b22-16-
InChi Key BBJDRANVVNBXAR-JWGURIENSA-N
PubChem CID 60171585
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

MS436 is a potent and selective BRD4 bromodomain inhibitor (Ki = 30-50 nM for BrD1). It displays 10-fold selectivity for BrD1 of BRD4 over BrD2 of BRD4.


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