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MS023

Type I Protein Arginine Methyltransferases inhibitor
Catalog #: B2575
SKU-Size Size Price Qty
B2575-5 5 mg
$135.00
B2575-25 25 mg
$535.00
More Sizes Get Quote

Product Details

Alternate Name N1-((4-(4-isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine, MS-023
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 1831110-54-3
Molecular Formula C₁₇H₂₅N₃O
Molecular Weight 287.41
Purity ≥98% by HPLC
Solubility >25 mg/ml in DMSO
SMILES CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN
InChi InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3
InChi Key FMTVWAGUJRUAKE-UHFFFAOYSA-N
PubChem CID 92136227
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

MS023 is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) (IC₅₀s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively). MS023 is completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases.


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