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MS-275 (Entinostat, SNDX-275)

A HDAC1 and HDAC3 inhibitor
Catalog #: 1590
SKU-Size Size Price Qty
1590-1 1 mg
$320.00
1590-5 5 mg
$915.00
More Sizes Get Quote

Product Details

Alternate Name Entinostat, SNDX-275
Appearance Crystalline solid
CAS # 209783-80-2
Molecular Formula C₂₁H₂₀N₄O₃
Molecular Weight 376.41
Purity ≥99% by HPLC
Solubility DMSO (38 mg/ml)
SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
InChi InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
InChi Key INVTYAOGFAGBOE-UHFFFAOYSA-N
PubChem CID 4261
MDL Number MFCD08272435
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Preferentially inhibits HDAC1 (IC₅₀ = 300 nM) over HDAC3 (IC₅₀ = 8 µM). Has no inhibitory activity towards HDAC8 (IC₅₀>100 µM).


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