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MPI-5a

A selective inhibitor of HDAC6
Catalog #: B2833
SKU-Size Size Price Qty
B2833-500 500 µg
$105.00
B2833-1000 1000 μg
$185.00
More Sizes Get Quote

Product Details

Alternate Name HDAC6 inhibitor; N-hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide; N-hydroxy-2-(1-methyl-1H-pyrrole-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide
Formulation A solution in acetonitrile
CAS # 1259296-46-2
Molecular Formula C₁₆H₁₇N₃O₃
Molecular Weight 299.32
Purity ≥95%
Solubility ~30 mg/ml in Ethanol, DMSO and DMF
SMILES CN1C=CC=C1C(=O)N2CCC3=C(C2)C=CC(=C3)C(=O)NO
InChi InChI=1S/C16H17N3O3/c1-18-7-2-3-14(18)16(21)19-8-6-11-9-12(15(20)17-22)4-5-13(11)10-19/h2-5,7,9,22H,6,8,10H2,1H3,(H,17,20)
InChi Key NNQAQGDSGCGFER-UHFFFAOYSA-N
PubChem CID 49831258
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

MPI-5a is a potent and selective inhibitor of Histone Deacetylase 6 (HDAC6) with an IC₅₀ of 36 nM. It inhibits the acetylation of tubulin in cells with an IC₅₀ value of 210 nM.


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