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MOTS-c (human)

An AMPK activator
Catalog #: 9697

Product Details

Cat # +Size 9697-1
Size 1 mg
Alternate Name H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH . TFA; Mitochondrial Open Reading Frame of the 12S rRNA-c; MOTS3
Appearance Lyophilized solid
CAS # 1627580-64-6
Molecular Formula C₁₀₁H₁₅₂N₂₈O₂₂S₂.C₂HF₃O₂
Molecular Weight 2288.6
Purity ≥95% by HPLC
Solubility H₂O
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


MOTS-c is a mitochondria-derived peptide (MDP) that promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK). Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice. Potential anti-obesity and anti-aging compound

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