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A cell-permeable glutathione probe
Catalog #: B2671
SKU-Size Size Price Qty
B2671-5 5 mg
B2671-25 25 mg
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Product Details

Alternate Name NSC602733; 7-(chloromethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione; NSC-602733; Chlorobimane
Appearance Yellow solid
CAS # 76421-73-3
Molecular Formula C₁₀H₁₁ClN₂O₂
Molecular Weight 226.66
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C10H11ClN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3
PubChem CID 114886
MDL Number MFCD00077379
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

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