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Moexipril hydrochloride

A potent angiotensin converting-Enzyme (ACE) inhibitor
Catalog #: B2134

In stock

SKU-Size Size Price Qty
B2134-5 5 mg
$75.00
B2134-25 25 mg
$225.00
More Sizes Get Quote

Product Details

Alternate Name (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid hydrochloride
Appearance Crystalline solid
CAS # 82586-52-5
Molecular Formula C₂₇H₃₅N₂O₇Cl
Molecular Weight 535.03
Purity ≥98% by HPLC
Solubility H₂O (30 mg/ml)
SMILES CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC.Cl
InChi InChI=1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1
InChi Key JXRAXHBVZQZSIC-JKVLGAQCSA-N
PubChem CID 54889
MDL Number MFCD00940481
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Moexipril is a prodrug of the long-acting angiotensin converting enzyme (ACE) inhibitor moexiprilat (IC₅₀s = 2.1 nM and 2.7 µM for moexiprilat and moexipril, respectively). In addition to its antihypertensive activity, moexipril has been identified as a phosphodiesterase 4 inhibitor (IC₅₀ = 38 µM for the PDE4B2 isoform) that increases cAMP in cells.


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