Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

MMP-14, Active, Human Recombinant

>90% Pure, Active, Human Recombinant MMP-14
Catalog #: 8009
SKU-Size Size Price Qty
8009-10 10 µg
8009-50 50 µg
More Sizes Get Quote

Product Details

Alternate Name Matrix metalloproteinase-14, MT1-MMP
Gene Symbol MMP14
Gene ID 4323
Accession # P50281
Source E. coli
Appearance Lyophilized powder
Physical Form Description Lyophilized from propriety buffer
Molecular Weight ~ 24.0 kDa (112-318 aa)
Purity by SDS-PAGE ≥90%
Reconstitution Instructions Reconstitute with dH2O
Amino Acid Sequence 112-318 aa
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


The Matrix metalloproteinase-14 (MMP-14) belongs to a family of zinc-dependent endopeptidases. The ability of MMP-14 to degrade type I collagen, and activate pro-MMP-2 and pro-MMP-9 makes it a key enzyme in many physiological and pathological processes such as angiogenesis and tumor invasion. MMP-14 is structurally a multi-domain metalloenzyme, composed of a prodomain, a metal-binding catalytic domain, a hinge region, a hemopexin-like domain, a transmembrane domain, and a cytoplamasic tail. The catalytic, and hinge domains of MT1-MMP were expressed in Escherichia coli and the active form was generated by successive autoproteolysis of the N- and C-terminal sites during refolding.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.