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MMP-13, Catalytic Domain, Human Recombinant

A Protein involved in breakdown of extracellular matrix
Catalog #: P1230

Product Details

Cat # +Size P1230-10
Size 10 μg
Alternate Name Collagenase 3, Matrix metalloproteinase, CLN-3
Gene Symbol MMP13
Gene ID 4322
Accession # P45452
Source E.coli
Appearance Lyophilized
Physical Form Description Proprietary Buffer
Molecular Weight 20.5 kDa
Purity by SDS-PAGE > 95%
Biological Activity Specific activity ≥200 mU/mg
Reconstitution Instructions Reconstitute the lyophilized protein in 30% glycerol to a final concentration 1.0 mg/ml and incubate the reconstituted protein at 25 °C for 15 minutes.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


MMP-13 is a member of the matrix metalloproteinase (MMP) family of enzymes. MMP enzymes are associated with remodeling and breaking down matrix proteins. Aberrant expressions of different MMP enzymes have been associated with periodontal disease, arthritis and caner metastasis. MMP-13 has been associated with breast cancer. This constitutively active MMP-13 lacks the inhibitory pro-domain and hemopexin domain.

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