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A Cancer Cell Stem cell inhibitor
Catalog #: 2515
SKU-Size Size Price Qty
2515-5 5 mg
2515-25 25 mg
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Product Details

Alternate Name (2E)​-​N-​​(4,​​5-​​dihydro-​​2-​​thiazolyl)​-​​3-​​(4-​​ethylphenyl)​-​2-​​propenamide; CID-50910523
Appearance White solid
CAS # 1426576-80-8
Molecular Formula C₁₄H₁₆N₂OS
Molecular Weight 260.35
Purity ≥98% by HPLC
Solubility DMSO (5 mg/ml)
InChi InChI=1S/C14H16N2OS/c1-2-11-3-5-12(6-4-11)7-8-13(17)16-14-15-9-10-18-14/h3-8H,2,9-10H2,1H3,(H,15,16,17)/b8-7+
PubChem CID 50910523
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


ML-243 is a selective inhibitor of cancer stem cells. Displays 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC₅₀ = 2.0 µM) over a control (mammary epithelial) cell line (EC₅₀ = 64 µM). It weakly antagonizes the adenosine A2A receptor (IC₅₀ = 10 µM) and has no effect on 68 other targets commonly used in drug discovery for lead profiling.

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