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Ml241

A potent, selective, and reversible AAA ATPase p97 inhibitor
Catalog #: 2697
SKU-Size Size Price Qty
2697-5 5 mg
$95.00
2697-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine;CID49830260
Appearance White to off-white solid
CAS # 1346528-06-0
Molecular Formula C₂₃H₂₄N₄O
Molecular Weight 372.46
Purity ≥98% by HPLC
Solubility DMSO
SMILES C1CCC2=C(C1)C(=NC(=N2)N3CCOC4=CC=CC=C43)NCC5=CC=CC=C5
InChi InChI=1S/C23H24N4O/c1-2-8-17(9-3-1)16-24-22-18-10-4-5-11-19(18)25-23(26-22)27-14-15-28-21-13-7-6-12-20(21)27/h1-3,6-9,12-13H,4-5,10-11,14-16H2,(H,24,25,26)
InChi Key RMZPVQQGYVSLAP-UHFFFAOYSA-N
PubChem CID 49830260
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC₅₀ = 100 nM). It blocks p97-dependent proteasome substrate with an IC₅₀ of ~ 3500 nM.


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