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ML239

A selective inhibitor of breast cancer stem cell
Catalog #: 2696
SKU-Size Size Price Qty
2696-5 5 mg
$105.00
2696-25 25 mg
$415.00
More Sizes Get Quote

Product Details

Alternate Name N'-[(Z)-pyrrol-2-ylidenemethyl]-2-(2,4,6-trichlorophenoxy)acetohydrazide; (2,4,6-Trichlorophenoxy)-acetic acid (1H-pyrrol-2-ylmethylene)-hydrazide; CID-49843203
Appearance White to off-white solid
CAS # 1378872-36-6
Molecular Formula C₁₃H10Cl₃N₃O₂
Molecular Weight 346.6
Purity ≥98% by HPLC
Solubility DMSO (~15 mg/ml)
SMILES C1=CC(=CNNC(=O)COC2=C(C=C(C=C2Cl)Cl)Cl)N=C1
InChi InChI=1S/C13H10Cl3N3O2/c14-8-4-10(15)13(11(16)5-8)21-7-12(20)19-18-6-9-2-1-3-17-9/h1-6,18H,7H2,(H,19,20)/b9-6-
InChi Key SZYDKEIZVCSYNB-TWGQIWQCSA-N
PubChem CID 49843203
MDL Number MFCD23098913
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

ML239 is a selective inhibitor of breast cancer stem cells. It inhibits cancer stem cells with an IC₅₀ of 1.16 μM with 24-fold selectivity against the control cell line. ML239 alters the expression of genes in the MAPK, NF-κB, and inflammatory cytokine pathways.


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