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Product Details
| Alternate Name | N'-[(Z)-pyrrol-2-ylidenemethyl]-2-(2,4,6-trichlorophenoxy)acetohydrazide; (2,4,6-Trichlorophenoxy)-acetic acid (1H-pyrrol-2-ylmethylene)-hydrazide; CID-49843203 |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 1378872-36-6 |
| Molecular Formula | C₁₃H10Cl₃N₃O₂ |
| Molecular Weight | 346.6 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (~15 mg/ml) |
| SMILES | C1=CC(=CNNC(=O)COC2=C(C=C(C=C2Cl)Cl)Cl)N=C1 |
| InChi | InChI=1S/C13H10Cl3N3O2/c14-8-4-10(15)13(11(16)5-8)21-7-12(20)19-18-6-9-2-1-3-17-9/h1-6,18H,7H2,(H,19,20)/b9-6- |
| InChi Key | SZYDKEIZVCSYNB-TWGQIWQCSA-N |
| PubChem CID | 49843203 |
| MDL Number | MFCD23098913 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
ML239 is a selective inhibitor of breast cancer stem cells. It inhibits cancer stem cells with an IC₅₀ of 1.16 μM with 24-fold selectivity against the control cell line. ML239 alters the expression of genes in the MAPK, NF-κB, and inflammatory cytokine pathways.
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