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ML-324

AJMJD2 histone demethylase inhibitor
Catalog #: 2763
SKU-Size Size Price Qty
2763-1 1 mg
$75.00
2763-5 5 mg
$285.00
More Sizes Get Quote

Product Details

Alternate Name N-(3-(dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
Appearance Light brown solid
CAS # 1222800-79-4
Molecular Formula C₂₁H₂₃N₃O₂
Molecular Weight 349.43
Purity ≥98% by TLC
Solubility DMSO (~ 20 mg/ml, warm) or EtOH (~ 6 mg/ml, warm)
SMILES OC1=CC(C2=CC=C(C(NCCCN(C)C)=O)C=C2)=CC3=CC=CN=C31
InChi InChI=1S/C21H23N3O2/c1-24(2)12-4-11-23-21(26)16-8-6-15(7-9-16)18-13-17-5-3-10-22-20(17)19(25)14-18/h3,5-10,13-14,25H,4,11-12H2,1-2H3,(H,23,26)
InChi Key QDBVSOZTVKXUES-UHFFFAOYSA-N
MDL Number MFCD28053518
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. ML-324 is a JMJD2 histone demethylase inhibitor (JMJD2 IC₅₀ = 920 nM). Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC₅₀ ~ 10 µM) and abrogates infection. Represses the reactivation of HSV from the latent state in sensory neurons.


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